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Allergic contact dermatitis due to the β ‐blocker betaxolol in eyedrops, with cross‐sensitivity to timolol
Author(s) -
Nino Massimiliano,
Napolitano Maddalena,
Scalvenzi Massimiliano
Publication year - 2010
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.2010.01721.x
Subject(s) - timolol , betaxolol , medicine , section (typography) , library science , ophthalmology , dermatology , humanities , art , glaucoma , advertising , computer science , business
A 59-year-old man, with no history of atopy or allergy, had long been treated for open-angle glaucoma with eyedrops containing the β-blocker betaxolol (Betoptic®) when he developed acute eyelid dermatitis, associated with conjunctival hyperaemia (Fig. 1). His condition rapidly improved after withdrawing betaxolol and using topical corticosteroids. Patch testing with the European baseline series, a preservatives series, and ophthalmic medicaments series (including no β-blockers) was negative. On patch testing with the patient’s own ophthalmic medicaments and then with ophthalmic medicaments containing betaxolol or other β-blockers, the positive reactions in Table 1 were found.