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Patients with airborne sensitization/contact dermatitis from budesonide‐containing aerosols ‘by proxy’
Author(s) -
Baeck Marie,
Goossens AN
Publication year - 2009
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.2009.01575.x
Subject(s) - budesonide , sensitization , medicine , dermatology , allergic contact dermatitis , contact dermatitis , inhalation , context (archaeology) , allergy , immunology , anesthesia , paleontology , biology
Background: Inhalation corticosteroids (CSs), despite their wide use, rarely cause sensitization in subjects administering them. Objective: To determine the cause of sensitization and/or of allergic contact dermatitis which occurred in air‐exposed body areas of patients reacting to corticosteroids and to budesonide, in particular. Methods: We reviewed the patch test results and sensitization sources in patients who reacted positively to corticosteroids tested in the K.U. Leuven Dermatology department during an 18‐year period. Results: Fifteen subjects, not themselves treated by budesonide‐containing aerosols, but taking care of/or living together with patients who used them because of a chronic respiratory affection, appeared to have been sensitized by airborne exposure and/or presented with airborne allergic contact dermatitis from them. Conclusion: Air exposure to inhalation corticosteroids used ‘by proxy’ and to budesonide, in particular, needs to be taken into account as a potential cause of primary sensitization and/or airborne allergic contact dermatitis, sometimes also in an occupational context.