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Allergic contact dermatitis from oleyl alcohol in Elidel ® cream
Author(s) -
Andersen Klaus Ejner,
BroesbyOlsen Sigurd
Publication year - 2006
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.2006.00948.x
Subject(s) - dermatology , medicine , allergic contact dermatitis , contact dermatitis , atopic dermatitis , allergy , oleyl alcohol , irritant contact dermatitis , tacrolimus , hand dermatitis , patch test , pimecrolimus , alcohol , immunology , surgery , chemistry , biochemistry , transplantation
We report an atopic dermatitis patient with recurrent hand dermatitis who developed a severe allergic contact dermatitis from the use of Elidel ® cream. Diagnostic patch tests showed an isolated contact allergy to the emulsifier oleyl alcohol present in the product. Pimecrolimus appeared to have had an aggravating effect on the dermatitis in spite of its immunosuppressive effects. The initial clinical appearance of the patient’s widespread dermatitis was atypical with resemblance to subacute cutaneous lupus erythematosus. Even though emulsifiers are widely used in topical products, contact allergic reactions to these are relatively uncommon.