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Occupational allergic contact dermatitis from isophoronediamine (IPDA) in operative‐clothing manufacture
Author(s) -
Tarvainen Kylliki,
Jolanki Riitta,
Eckerman MajLen Henriks,
Estlander Tuula
Publication year - 1998
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1998.tb05826.x
Subject(s) - epoxy , allergic contact dermatitis , contact dermatitis , allergy , coating , dermatology , materials science , composite material , medicine , immunology
Isophoronediamine (IPDA), 3‐amino‐methyl‐3,5,5‐tri‐methylcyclohexylamine, is a cycloaliphatic epoxy resin hardener (CAS 2855‐13‐2). It is a well‐known human sensitizer (1–6), and has also been shown to be an extremely strong sensitizer by the guinea pig maximization test (7). In addition, IPDA is a cause of occupational asthma (5). Contact allergy to IPDA has been reported from epoxy floor‐laying (2, 8), painting (5), manufacture of tennis rackets (1) and epoxy floor coating (5).