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Iodopropynyl butylcarbamate: a new contact allergen
Author(s) -
Bryld Lars Erik,
Agner Tove,
Rastogi Suresh C.,
Menné Turkil
Publication year - 1997
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1997.tb00400.x
Subject(s) - patch testing , contact allergy , medicine , contact dermatitis , allergic contact dermatitis , cosmetics , patch test , dermatology , allergen , allergy , surgery , immunology , pathology
Iodopropynyl butylcarbamate (IPBC) has been used for years as a fungicide and bactericide for wood and paint preservation without any reports of cutaneous side‐effects. During the last few years, it has entered cosmetic products and is temporarily permitted in the EU Cosmetics Directive in a use concentration of 0.1%. In the present study, we report our preliminary experience with patch testing consecutive contact dermatitis patients with IPBC. A patch lest concentration of 0.1% seems appropriate for initial screening but deserves further evaluation. Among 311 consecutive patch lest patients. 3 patients with a positive patch lest to IPBC have been identified. Contact allergy is Likely in at least 1 case, based on clinical history, exposure history, patch testing with dilution series. ROAT and chemical analysis.