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Discrepancy in patch test results with wool wax alcohols and Amerchol® L‐101
Author(s) -
Matthieu L.,
Dockx P.
Publication year - 1997
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1997.tb00398.x
Subject(s) - wax , wool , lanolin , patch test , contact allergy , chemistry , contact dermatitis , allergy , chromatography , organic chemistry , medicine , materials science , composite material , immunology
Wondering why Amerchol® L‐101 (containing wool wax alcohols obtained from the hydrolysis of wool fall appears as a test material (100%) in a cosmetics series (Chemotechnique Diagnostics AB). as wool wax alcohols were already tested in the European standard series, we added Amerchol®L‐101 (100%) systematically to the standard series, From 8 April 1991 to 28 February 1992. a total of 393 patients were tested: 3.05% ( n = l2) showed positive test results (+, ++, +++) for wool wax alcohols as well as Amerchol® L‐101 (100%.), only and 11.1% ( n = 44) for Amerchol® L‐101 (100%) only. Thus, the positive tests for Amerchol® L‐101 (100%) had a higher frequency of 3.4 compared to those for wool wax alcohols. In the meantime, we also added Amerchol® L‐101 50% (Trolab) to the standard series. Of all patients tested ( n =223) 2.7% ( n =6) had positive reactions to wool wax alcohols and 12.1% ( n =27) to Amerchol® L‐101 100% and or 50%. Thus, positive reactions to Amerchol® L‐101 (100% and 50%) were 45 higher, whereas the rate of concordancy decreased. It is remarkable that 8 patients only had a positive reaction to Amerchol® L‐101 50% and 9% only to Amerchol® L‐101 1005. It seems that we miss many diagnoses in contact allergy by using only the standard wool wax alcohols test (30%)