Premium
Tolerance to intravenous admiration of heparin and heparinoid in a patient with delayed‐type hypersensitivity to heparins and heparinoids
Author(s) -
Boehncke WolfHenning,
Weber Lutz,
Gall Helmut
Publication year - 1996
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1996.tb02293.x
Subject(s) - heparinoid , medicine , heparin , provocation test , delayed hypersensitivity , pharmacology , anesthesia , surgery , immunology , pathology , alternative medicine , antigen
Delayed‐type hypersensitivity reactions ot subcutaneously (s.c) injected heparins are common. Since similar reactions usually occur to different heparin preparations, semisynthetic heparinoids might be a therapeutic alternative. We report a patient exhibiting eczematous reactions to heparins as well as heparinoids; delayed‐type hypersensitivity was demonstrated by intracutaneous (i.c.) and patch tests, as well as by s.c. provocation. Remarkably, intravenous (i.v.) administration of heparin as well as heparinoid was well‐tolerated.