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Corticosteroid contact hypersensitivity: what vehicle and concentration?
Author(s) -
Wilkinson S. M.,
Beck M. H.
Publication year - 1996
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1996.tb02212.x
Subject(s) - budesonide , patch testing , corticosteroid , allergic contact dermatitis , patch test , medicine , dermatology , contact dermatitis , ethanol , allergy , chemistry , surgery , immunology , organic chemistry
The correct concentration and vehicle for patch Letting with corticosteroids is in many instances not known. Tine results of this study Suggest that 1% in ethanol should be the initial choice, unless it can he shown that petrolatum as a vehicle is as sensitive (tixocortol pivalate and budesonide). We could find no evidence for the anti‐inflammatory effects of corticosteroids inhibiting the patch test al higher concentrations. Using ethanol as the vehicle resulted in reactions developing at earlier time points than with petrolatum.