Premium
Delayed hypersensitivity at the injection sites of a low‐molecular‐weight heparin
Author(s) -
Moreau A.,
Dompmartin A.,
Esnault P.,
Michel M.,
Leroy D.
Publication year - 1996
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1996.tb02108.x
Subject(s) - heparin , low molecular weight heparin , medicine , allergy , subcutaneous injection , delayed hypersensitivity , hypersensitivity reaction , anesthesia , surgery , immunology , immune system
We report a case of delayed hypersensitivity to a low‐molecular‐weight heparin. The patient presented with eczema at the site of subcutaneous injections and allergy testes confirmed the clinical diagnosis. There were positive tests with 3 low‐molecular‐weight heparins and unfractionated subcutaneous calcium heparin but negative with intravenous sodium heparin. Although delayed hyper‐sensitivity to low‐molecular‐weight heparins is rare, the possibility of cross‐allergy to unfractionated heparin could be a therapeutic problem for some patients.