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Occupational allergic contact dermatitis from 2‐hydroxyethyl methacrylate and ethylene glycol dimethacrylate in a modified acrylic structural adhesive
Author(s) -
Kanerva Lasse,
Jolanki Riitta,
Leino Timo,
Estlander Tuula
Publication year - 1995
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1995.tb00506.x
Subject(s) - acrylate , methacrylate , ethylene glycol dimethacrylate , allergic contact dermatitis , adhesive , polymer chemistry , 2 hydroxyethyl methacrylate , chemistry , allergy , polymerization , organic chemistry , copolymer , medicine , polymer , methacrylic acid , immunology , layer (electronics)
Acrylates have a broad area of application in various products including glues, sealants and adhesives. Whereas anaerobic acrylic sealants arc well‐known sensitizers, acrylate glues that cure in air have only seldom been reported as allergens. Here a patient sensitized to such a glue, and developing hand dermatitis that spread to the lower arms, chest, neck and face, is presented. Her glue was analyzed by gas chroma tography/mass spectrometry (GC/MS) and contained 24,6% 2‐hydroxyethyl methacrylate (2‐HEMA) and 0.4% ethylene glyol dimethacrylate (EGDMA). These 2 acrylate compounds, as well as her glue, provoked an allergic patch test reaction. Also many other acrylate compounds, e.g., tetrahydrofurfuryl methacrylate, gave an allergic reaction indicating cross‐allergy. The patient could not continue in her previous workplace because of severely‐relapsing skin symptoms.