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Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer
Author(s) -
Hausen B. M.
Publication year - 1993
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1993.tb03532.x
Subject(s) - centella , medicine , traditional medicine , dermatology , contact dermatitis , allergy , immunology
The sensitizing capacity of Centella asiatica (raw extract) and its triterpenic constituents asiaticoside, asiatic acid and madecassic acid has been studied in guinea pigs. The extract itself as well as the 3 acids were found to be very weak sensitizers. Centella asiatica extract is used effectively in the treatment of keloids, leg ulcers, phlebitis, slow‐healing wounds, leprosy, surgical lesions, striae distensae and cellulitis. Athough applied frequently to damaged skin, the risk of acquiring contact sensitivity to this plant or its constituents is low.