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Influence of area of application of allergen on sensitization in contact dermatitis
Author(s) -
Upadhye Monika R.,
Maibach Howard I.
Publication year - 1992
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1992.tb03280.x
Subject(s) - allergen , sensitization , allergic contact dermatitis , contact dermatitis , medicine , allergy , dermatology , immunology
There are at lest 2 quantitative variables when applying allergens to obtain sensitization the absolute amount of allergen and the surface concentration. This review analyzes the limited studies on surface concentration and determines surface area threshold levels for the allergens documented in the literature.