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Patch test responses to rockwool of different diameters evaluated by cutaneous blood flow measurement
Author(s) -
Eun H. C.,
Lee H. G,
Paik N. W.
Publication year - 1991
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1991.tb01721.x
Subject(s) - patch test , laser doppler velocimetry , irritation , skin irritation , biomedical engineering , blood flow , surgery , medicine , dermatology , allergy , immunology
Rockwool is a man‐made mineral fiber used mainly for insulation, which can cause mechanical skin irritation. This study was performed to evaluate the irritant potential of rockwools of different diameters and to compare the change of blood flow, measured by laser Doppler flowmetry, at different patch test occlusion times with rockwools. Rockwool A(mean diameter 4.20 ± 1.96 μ) was more irritating than rockwool B (mean diameter 3.20 ± 1.5 μ). The difference was more clearly observed in a 48‐h patch test than in an 8‐h or 24‐h test. We consluded that laser patch test responses to mechanical irritants like rockwool, and that 48 h or more of occlusion time was necessary to produce irritant patch test responses to certain types of rockwool.