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Systemic contact dermatitis from pseudoephedrine
Author(s) -
Tomb Roland R.,
Lepoittevin JeanPierre,
Espinassouze François,
Heid Ernest,
Foussereau Jean
Publication year - 1991
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1991.tb01657.x
Subject(s) - pseudoephedrine , nasal decongestant , ephedrine , dermatology , medicine , contact dermatitis , phenylephrine , patch test , allergic contact dermatitis , hydrochloride , anesthesia , epinephrine , allergy , chemistry , organic chemistry , immunology , blood pressure
A patient with rhinitis developed systemic contact dermatitis when starting oral treatment with Rhinalair®, Containing pseudoephedrine hydrochloride. A few months later, another oral treatment Rinutan®, containing norephedrine hydrochloride, provoked a more severe generalized eczema. Patch test reactions were strongly positive to ephedrine and pseudoephedrine, slightly positive to phenylephrine and negative to epinephrine. Norephedrine was not tested.