Premium
The nickel content of certain commercially available metallic patch test materials and its relevance in nickel‐sensitive subjects
Author(s) -
Eedy D. J.,
Burrows D.,
Mcmaster Dorothy
Publication year - 1991
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1991.tb01622.x
Subject(s) - nickel , patch test , patch testing , materials science , metallurgy , contact dermatitis , medicine , allergy , immunology
The nickel contamination of the metallic patch test substance from 3 commercial sources was estimated by atomic absorption spectrophotometry. Contamination was generally greatest in the cobalt patch test substances. To determine whether the levels of contamination encountered were sufficient to produce a false positive patch test, 20 nickel‐sensitive patients were patch tested to various concentrations of free elemental nickel in aqueous solution. The level of nickel contamination was less than that required to produce a false positive patch test in our patients, but was at a level which could produce false positive reactions in subjects highly sensitive to nickel.