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Phototoxicity due to Cachrys libanotis
Author(s) -
Ena P.,
Cerri R.,
Dessi G.,
Manconi P. M.,
Atzei A. D.
Publication year - 1991
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1991.tb01620.x
Subject(s) - phototoxicity , furocoumarins , identification (biology) , chemistry , pharmacology , medicine , dermatology , biology , photochemistry , biochemistry , botany , in vitro
After classification and identification of the plant, the alcoholic extract of Cachrys libanotis L. was analysed in order to identify the phototoxic agents. The substances responsible for photodermatitis were found to be 4 furocoumarins, of which 3 have been clearly identified, namely 5‐methoxy‐, 8‐methoxy‐and 5,8‐dmiethoxypsoralen. The structure of a 4th compound was not completely defined.