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The use of laboratory methods in contact dermatitis induced by composite materials
Author(s) -
Ayala Fabio,
Lembo Giuseppe,
Balato Nicola,
Patruno Cataldo,
Scognamiglio Gennaro,
Strazzullo Giuseppe,
Stefano Salvatore
Publication year - 1990
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1990.tb01593.x
Subject(s) - contact dermatitis , allergic contact dermatitis , chemistry , abietic acid , hapten , chromatography , dermatology , epoxy , organic chemistry , rosin , allergy , medicine , immunology , antigen , resin acid
Thin‐layer chromatography, column chromatography, new spectrometry and nuclear magnetic resonance were used to investigate the chemical constituents and haptens responsible in 2 different circumstances where allergic contact dermatitis from composite materials was suspected. In an aircraft factory where epoxy resins were used, tetraglycidyl‐4,4‐dimythyl dianiline and phenylglycidyl ether were identified as the haptens responsible for an outbreak of contact dermatitis. The role of abietic acid as the main sensitizer in colophony was confirmed in a case of contact dermatitis occurring in a sportsman with an acute eczematous reaction due to a leg bandage. Identification of the chemical sensitizers was possible only by using the aforementioned laboratory methods.