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Wood tars allergy, cross‐sensitization and coal tar
Author(s) -
Roesyanto I. D.,
Akker Th. W.,
Joost Th. W.
Publication year - 1990
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1990.tb01524.x
Subject(s) - sensitization , allergy , dermatology , tar (computing) , coal tar , medicine , coal , immunology , chemistry , organic chemistry , computer science , programming language
In a population of 1883 patients tested for allergic contact dermatitis (1985–1988), a prevalence of 5.4%(103 cases) was seen for wood tars (ICDRG allergen, 12% pet.) sensitization. In this group ( n =103), retrospectively, a combined allergy was seen to wood tars and fragrance mix in 43% and to wood tars and balsam of Peru in 31%. A combined allergy to wood tars and coal tar was seen in 19 patients (18.5%); 14 to liquor carbonis detergens (LCD), 8 to lianthral and 3 to both LCD and lianthral. Within the group with wood tars allergy ( n =103), a minority ( n = 37) had a history of atopic dermatitis. Comparison of the test results in atopic and non‐atopic subgroups (within the group of 103) revealed a higher incidence of combined wood tars‐fragrance mix allergy in the atopic group ( n = 37). In this group, a lower incidence of combined wood tars‐coal tar sensitization was seen in comparison with the non‐atopic group ( n = 66). The authors believe that combined “wood tars‐coal tar” allergy could be the consequence of cross‐sensitization rather than due to long‐term previous topical treatment with tar derivatives. The high% of cross‐allergy between wood tars and fragrance mix emphasizes the role of wood tars as an important indicator allergen in perfume allergy.