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An epidemiological study of contact allergy to 5‐chloro‐3‐methyl isothiazolone/3‐methyl isothiazolone in Strasbourg
Author(s) -
Foussereau J.
Publication year - 1990
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1990.tb01519.x
Subject(s) - allergy , medicine , contact allergy , patch test , nickel allergy , incidence (geometry) , preservative , allergic contact dermatitis , contact dermatitis , dermatology , surgery , immunology , chemistry , organic chemistry , physics , optics
In Strasbourg, the incidence of allergy lo the mixture of 5‐chloro‐3‐methyl isothiazolone and 3‐methyl isothiazolone(MCI) in 540 patients (313 women and 227 men), routinely tested with this preservative as part of the standard series of allergens, was 1.11%. The frequency was 1.6% in women and 0.44% in men. A total of 6 cases of allergy, 5 in women and 1 in a man, to MCI were detected. In 5 cases out of 6, the patient was shown to have used cosmetic products containing this preservative. Finally in 5 cases out of 6, the subjects allergic to MCI also tested positively for nickel, while only 15% of the total of 540 subjects tested with MCI had a nickel allergy confirmed by patch tests.