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Allergic contact dermatitis from croconazole hydrochloride
Author(s) -
Shono Mamiko,
Hayashi Ken,
Sugimoto Rie
Publication year - 1989
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1989.tb03200.x
Subject(s) - allergic contact dermatitis , contact dermatitis , dermatology , medicine , hydrochloride , patch testing , drug , contact allergy , allergy , patch test , pharmacology , chemistry , immunology , organic chemistry
We report 6 cases of contact sensitivity to croconazole hydrochloride, a new imidazole antimycotic drug introduced to the Japanese market in 1986. and available as 1% gel and cream, 6 sensitized patients reacted on patch testing in cruconazole hydrochloride down to 0.5 to 0.1% pet, and 3 appeared to be cross‐sensitized to sulconazole nitrate. In Japan, allergic contact dermatitis to this drug has now been detected in 12 cases, including our own 6. Prescribes should be aware of contact sensitivity lo this drug.