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Sensitization to Kathon CG in Geneva and Switzerland
Author(s) -
Pasche Florence,
Hunziker Nicole
Publication year - 1989
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1989.tb03118.x
Subject(s) - sensitization , contact dermatitis , dermatology , medicine , allergy , immunology
Between October 1986 and June 1987 we patch tested 420 patients with Kathon CG at 100 ppm and obtained 23 positive reactions (5.5%). The other 5 Swiss university clinics joined our study between January and June 1987 and obtained sensitization rates ranging from 0.7 to 7.5%. The total mean value including Geneva was 3.6%. We did threshold patch testing in 12 patients with the following Kathon CG dilutions: 100, 50, 25, 15 and 7 ppm. We observed progressively diminishing skin reactions, especially below 25 ppm, but we still obtained slight positive reactions in 2 patients with Kathon CG at 7 ppm. Those reactions were relevant because the dermatitis disappeared when the: use of Kathon‐containing creams was discontinued.