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European multicenter study of the TRUE Test™
Author(s) -
Lachapelle J.M.,
Bruynzeel D. P.,
Ducombs G.,
Hannuksela M.,
Ring J.,
White I. R.,
Wilkinson J.,
Fischer T.,
Billerg K.
Publication year - 1988
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1988.tb05504.x
Subject(s) - patch test , concordance , test (biology) , contact dermatitis , medicine , dermatology , skin test , allergic contact dermatitis , contact allergy , surgery , multicenter study , allergy , pathology , immunology , biology , randomized controlled trial , paleontology , tuberculosis
A new, standardized, ready‐to‐apply patch test, the TRUE Test™, has been evaluated on 698 consecutive patients with suspected contact dermatitis. The patients were tested with 12 different allergens. Simultaneously, the same 12 allergens in pet. (Trolab®) were applied symmetrically to the opposite side of the upper back using the conventional Finn Chamber® technique. There were positive test reactions to all 12 allergens lusted in the patient group. The concordance of positive reactions between the TRUE Test™ and the Finn Chamber® test was 67%; 13% of all positive reactions were recorded only for the TRUE Test™ and 20% only for the Finn Chamber® method. The frequency of questionable and irritant reactions was of the same low order of magnitude for both tests methods; such reactions were recorded an around 2% of all test patches.