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Sensitization studies in the guinea pig with the active ingredients of Euxyl® K 400
Author(s) -
Bruze Magnus,
Gruvberger Birgitta,
Agrup Gun
Publication year - 1988
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1988.tb05487.x
Subject(s) - guinea pig , sensitization , active ingredient , preservative , skin sensitization , medicine , pharmacology , chemistry , immunology , food science
The preservative Euxyl® K 400 consists of the 2 active ingredients, 2‐phenoxyethanol and 1, 2‐dibromo‐2, 4‐dicyanobutane. Sensitization studies with the guinea pig maximization test were performed with these substances, but no sensitizing capacity was demonstrated in the case of either compound.