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Trends in allergic contact sensitization
Author(s) -
Gollhausen Rainer,
Enders Friedemann,
Przybilla Bernhard,
Burg Günter,
Ring Johnannes
Publication year - 1988
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1988.tb04501.x
Subject(s) - potassium dichromate , paraben , patch test , contact dermatitis , sensitization , thiomersal , chemistry , turpentine , lanolin , allergy , medicine , immunology , chromatography , preservative , organic chemistry
A standard patch test series was tested for 7 years (1977–1983) in a total of 11,962 patients. The annual frequency of positive reactions to the compounds tested was assessed for the total and for males and females separately. During the observation period, there were significant increases in positive reactions in the total group from 6.2% to 12.7% for nickel sulphate. from 5,3% lo 7.0% fur balsam of Peru and from 3.8% to 6.5% for potassium dichromate, reflecting significant changes in both sexes. The frequency of positive reactions to wool alcohols, formaldehyde, neomycin sulphate, paraben mix and gentamycin sulphate significantly increased, while that of positive reactions to clioquinol, mercuric chloride arid turpentine peroxide significantly decreased in cither males or females, sometimes leading to significantly changes in the total group.