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Rubber contact urticaria
Author(s) -
Turjanmaa Kristhna,
Laurila Kaija,
MäkinenKiljunen Soili,
Reunala Timo
Publication year - 1988
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1988.tb02953.x
Subject(s) - natural rubber , surgical gloves , polyvinyl chloride , contact urticaria , medicine , allergen , contact dermatitis , surgery , dermatology , allergy , chemistry , immunology , organic chemistry
To compare the immediate skin test reactivity of various latex (natural rubber) surgical and cleaning gloves. prick tests were performed on 40 latex‐allergic persons, 26 of whom were sensitized by surgical and 14 by cleaning latex gloves. 6/17 surgical gloves tested and 1/2 cleaning gloves caused positive reactions in almost all (over 87%) of the allergic subjects. In contrast. the frequencies of positive reactions to 4 other surgical latex gloves were us low as 8–21%, suggesting that not all surgical gloves arc equally allergenic. Control prick tests with I synthetic rubber and 1 polyvinyl chloride (PVC) glove were negative in all subjects. 2 surgical latex gloves causing either a high or low number of positive prick tests in allergic subjects were analyzed with high‐pressure liquid chromatography (HPLC). Similar allergenic protein fractions were detected, which showed protein peaks at MW 2000 5000 and 3000 daltons. Corresponding proteins were detected in I latex cleaning glove analyzed and in natural rubber. This result confirms that allergnic proteins persist in various surgical and cleaning latex gloves after manufacture from natural rubber and may cause contact, urticaria symptoms toms in sensitized people.