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Generalized eruption with severe liver dysfunction associated with occupational exposure to trichloroethylene
Author(s) -
Nakayama Hiroko,
Kobayashi Misaki,
Takahashi Masaru,
Ageishi Yoshio,
Takano Takehito
Publication year - 1988
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1988.tb02867.x
Subject(s) - trichloroethylene , dermatology , medicine , occupational exposure , contact dermatitis , patch test , immunology , chemistry , allergy , environmental health , environmental chemistry
Generalized dermatitis due to trichloroethylene is rare. A 21‐year‐old printer developed exfoliative dermatitis with mucous membrane involvement, fever and liver dysfunction after a 2‐week occupational exposure to trichloroethylene. Positive patch‐test reactions in trichloroethylene and to one of its metabolites, trichloroethanol, were observed. This dermatitis is considered to be mediated by a delayed‐type hypersensitivity mechanism