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Allergenic agent in contact dermatitis from Holigarna ferruginea
Author(s) -
Srinivas C. R.,
Kulkarni S. B.,
Me S. K.,
Krupashankar D. S.,
Iyengar M. A.,
Singh K. K.,
Sequeira R. P.,
Holla K. R.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb02716.x
Subject(s) - contact dermatitis , exudate , allergic contact dermatitis , patch test , medicine , acetone , dermatology , traditional medicine , asymptomatic , patch testing , allergy , chemistry , immunology , surgery , organic chemistry , pathology
9 of 10 patients who developed dermatitis following contact with Holigarna ferruginea and 5 of 35 asymptomatic volunteers showed a positive patch test reaction to 2% W/V acetone extract of the plant's resinous exudate. 6 albino rats were sensitized following 3 weekly applications of the same extract. Laccol (3‐heptadecadienyl catechol) was identified as the active principle in the exudates.