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Propolis allergy
Author(s) -
Husen B. M.,
Wollenweber E.,
Senff H.,
Post B.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb02700.x
Subject(s) - propolis , cosmetics , allergen , contact dermatitis , allergy , caffeic acid , allergic contact dermatitis , traditional medicine , chemistry , food science , medicine , organic chemistry , immunology , antioxidant
As shown in the preceding paper, propolis or bee‐pine is the cause of an increasing number of allergic reactions in persons using it in external preparations and cosmetics. Propolis und its main contact allergen, 1,1‐dimethylallyl caffeic acid ester, designated LB‐1, show strong sensitizing properties in properties as well as in guinea pig experiments. 9 patients have been patch tested with this compound, 8 of whom reacted strongly. Chemical separation of different propolis samples and poplar and extracts reveal that LB‐1 is always present. Poplar bud secretion is the bee's major source for propolis und hence the origin of LB‐1. A warning is indicated, in agreement with several other authors, that propolis should not be used in topical products because of its strong sensitizing properties.