Premium
Allergic and irritant contact dermatitis from falcarinol and didehydrofalcarinol in common ivy ( Hedera helix L.)
Author(s) -
Hausen B. M.,
Bröhas J.,
König W. A.,
Faasch H.,
Hahn H.,
Bruhn G.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb02634.x
Subject(s) - hedera helix , araliaceae , allergic contact dermatitis , irritant contact dermatitis , allergen , ginseng , chemistry , traditional medicine , contact dermatitis , botany , allergy , medicine , biology , immunology , alternative medicine , pathology
Experimental and chemical investigations revealed that common ivy ( Hedera helix susp. Helix ) contains 3 compounds which are powerful irritants and moderate sensitizers. Only 2 of these constituents, falcarinol and didehydrofalcarinol, are present in the plant during the whole year. Besides Panax ginseng and Schefflera arboricala , this is the third species of the Araliaceae in which these polyacetylenic sensitizers have been found. Falcarinol and didehydrofalcarinol also occur in Hedera helix subsp. canariensis. 4 patients have been patch tested. Even in low concentrations (0.03%). the main allergen falcarinol elicited strong reactions in all of them. One of the authors became sensitized during the investigations.