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Occupational dermatitis in bakers: a clue for atopic contact dermatitis
Author(s) -
Pigatto P. D.,
Polenghi M. M.,
Altomare G. F.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb01450.x
Subject(s) - atopic dermatitis , medicine , immunoglobulin e , dermatology , contact dermatitis , patch test , immunology , allergy , monoclonal antibody , atopy , irritant contact dermatitis , immunohistochemistry , allergic contact dermatitis , immunopathology , antibody , pathology
6 patients are described who developed contact dermatitis after cereal contact on atopic skin for periods of 2 to 20 years. 2 patients were wheat flour patch‐test‐positive. They had punch biopsies taken for standard histological and immunohistochemical investigation by labeling with monoclonal antibodies. anti‐DR and anti‐IgE. Sections showed features of contact dermatitis. There were many dendritic cells located perivascularly in the papilla and in the epidermidis, intensely positive for monoclonal anti‐IgE antibody. In control atopic subjects, there were a few perivascular IgE positive cells, probably mastocytes. This study shows that there may be a relationship between some allergens and atopic eczema in patients exposed to them in the course of their work. In some cases, there was a true allergic contact dermatitis, seen through the clinical and histological characteristics, and the results of immunohistochemical study.