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Patch test reactivity to nickel alloys
Author(s) -
Menné T.,
Brandrup F.,
ThestrupPedersen K.,
Veien N. K.,
Andersen J. R.,
Yding F.,
Valeur G.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb01448.x
Subject(s) - nickel , reactivity (psychology) , microgram , corrosion , patch test , nickel allergy , materials science , metallurgy , chemistry , contact dermatitis , allergy , medicine , immunology , in vitro , pathology , biochemistry , alternative medicine
11 widely used nickel alloys were investigated with respect to corrosion stability and reactivity in nickel‐sensitive individuals. Alloys with a nickel release in synthetic sweat exceeding 1 μg/cm 2 /week gave a strong patch test reaction in nickel‐sensitive persons; those with a release below 0.5 μg/cm 2 /week showed weak reactivity with one exception. Nickel allergy is a health problem. It may be minimized by using nickel alloys with a corrosion level below 0.5 μg/cm 2 /week. Action should be taken by dermatologists, industry and authorities to solve this neglected problem.