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Sensitization to methylenedianiline and para‐structures
Author(s) -
Joost Th.,
Helle F.,
Boer J.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb01446.x
Subject(s) - sensitization , allergy , skin sensitization , allergic contact dermatitis , medicine , contact dermatitis , dermatology , contact allergy , immunology , patch test
A toxic‐allergic skin reaction of the face, neck and arms due to accidental contact with methylenedianiline (syn: 4‐4′‐diaminodiphenylmethane) is reported in a cleaner at a chemical plant. Patch tests revealed sensitization to chemicals of the para‐group. Earlier exposure to it was unlikely. Previous sensitization to related chemicals and possible cross‐sensitization was considered to be the primary cause of the allergy and the clinical manifestations.