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Lipstick dermatitis due to C 18 aliphatic compounds
Author(s) -
Hayakawa Ritsuko,
Matsunaga Kayoko,
Suzuki Mari,
Arima Yaeno,
Ohkido Yukari
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb01428.x
Subject(s) - impurity , chemistry , contact dermatitis , patch testing , alcohol , organic chemistry , chromatography , dermatology , nuclear chemistry , medicine , allergy , immunology
An 18‐year‐old girl developed cheilitis. She had a past history of lip cream dermatitis, but the cause was not found. Patch tests with 2 lipsticks were strongly positive. Tests with the ingredients were positive to 2 aliphatic compounds, glyceryl diisostearate and diisostearyl malate. Impurities in the materials were suspected as the cause. Analysis by gas chromatography detected 3 chemicals in glyceryl diisostearate and 1 in diisostearyl malate as impurities. Patch testing with the impurities and glyceryl monoisostearate 0.01% pet in glyceryl diisostearate and isostearyl alcohol 0.25% pet in diisostearyl malate were strongly positive. The characteristics common to the 2 chemicals were liquidity at room temperature, branched C 18 aliphatic compound and primary alcohol. Chemicals lacking any of the above 3 features did not react.