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The “edge effect” with patch test materials
Author(s) -
Fyad A.,
Masmoudi M. L.,
Lachapellh J. M.
Publication year - 1987
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1987.tb01409.x
Subject(s) - patch test , patch testing , test (biology) , allergic contact dermatitis , dermatology , contact allergy , contact dermatitis , chemistry , materials science , medicine , allergy , immunology , biology , botany
A positive “edge effect”, i.e., the accumulation on the skin of a chemical solution (such as fluorescein 0.01 % in a 50/50 water‐ethanol solution) at the periphery of the patch test sites has been demonstrated. It occurs with different test materials (Finn Chamber® Silver Patch Test: Patch Test Chamber®). Practical implications are discussed: this observation could be important when discussing results of laboratory investigations. In clinical practice, it could explain the occurence of “ring‐shaped” positive allergic patch test reactions to chemicals used in solution, i.e., Kathon CG® or hydrocortisone.