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Contact allergy to preservatives – II
Author(s) -
Groot Anton C.,
Bos Jan D.,
Jagtman Berend A.,
Bruynzeel Derk P.,
Joost Theodoor,
Weyland J. Willem
Publication year - 1986
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1986.tb01340.x
Subject(s) - preservative , allergy , formaldehyde , allergen , contact dermatitis , chemistry , contact allergy , patch test , dermatology , allergic contact dermatitis , alkyl , benzalkonium chloride , medicine , food science , organic chemistry , immunology
To determine whether the prevalence of allergic reactions to certain preservatives warrants their inclusion in a routine series for patch testing, a tray of 14 preservatives was tested in 501 consecutive suspected contact dermatitis patients. More than l% positive reactions were found with DMDM hydantoin. Kathon CG® and alkyl trimethyl ammonium chloride only. The concentration of alkyl trimethyl ammonium chloride (0.1% aqua) was considered too high. Of 6 patients reacting to the formaldehyde releaser DMDM hydantoin. 4 were positive to formaldehyde. Kathon CG® may be an important allergen in the Netherlands, and it is worthwhile for dermatologists there to add it to the standard test series. The recent inclusion afquaternium‐15 in the ICDRG standard series appears to be of little value to them.