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Sensitizing capacity of dihydroxydiphenyl methane (bisphenol F) in the guinea pig
Author(s) -
Bruze Magnus
Publication year - 1986
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1986.tb01230.x
Subject(s) - chemistry , formaldehyde , methane , phenol , organic chemistry
The sensitizing Capacity of 2,2 1 ‐ dihydroxydiphenyl methane (2,2 1 HPM). 4.4 1 – dihydroxydiphenyl methane (4,4 1 ‐ HPM) and 2.4 1 ‐ dihydroxydiphenyl methane (2,4 1 ‐ HPM) was investigated with the guinea pig maximization test. These compounds are known contact sensitizers in phenol‐formaldehyde resins. The study was performed to assess and Compare their sensitizing capacities. A weak sensitizing capacity of 2,2 1 ‐ HPM was demonstrated when the results for 2 separate series were added while no sensitizing capacity was demonstrated for 4.4 1 – HPM or 2,4 1 ‐HPM, The compounds tested were chromatographically pure.