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Allergic contact dermatitis due to a biocide containing 5‐chloro‐2‐methyl‐4‐isothiazohn‐3‐one
Author(s) -
Pilger Charles,
Nethercott James R.,
Weksberg Frederick
Publication year - 1986
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1986.tb01224.x
Subject(s) - biocide , allergic contact dermatitis , contact dermatitis , dermatology , allergy , medicine , immunopathology , immunology , pathology
3 cases of contact allergy due to the biocides 5‐chloro‐2‐methyl‐4‐isothiazolin‐3‐one and 2‐methyl‐4‐isothiazolin‐3‐one are reported 2 workers exposed to a soluble oil containing these 2 biocides experienced allergic contact dermatitis from them. The 3rd case was that of the chemist who separated the 2 materials for the execution of this Investigation. These compounds are chemically related to the biologically active components of Ectimar, Skane M‐8 and Proxel CRL. Further instances of contact allergy due lo these and related compounds are likely because of the apparently increasing use of such substances as antimicrobial agents in various commercial products.