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Epicutaneous induction of tolerance with acrylates and related compounds
Author(s) -
Parker Darien,
Long P.V.,
Bull J.E.,
Turk J.L.
Publication year - 1985
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1985.tb01084.x
Subject(s) - chemistry , acrylate , sensitization , propane , reactivity (psychology) , polymer chemistry , stereochemistry , organic chemistry , immunology , medicine , monomer , polymer , alternative medicine , pathology
Epicutaneous application of acrylates and related compounds 1.4 and 7 days before sensitization with either methyl acrylate or trimethylol propane triacrylate induced tolerates to the resultant contact reactions. This tolerance could not be correlated with either the degree of cross reactivity between these compounds or with their ability lo react covalently with ammo or sulphydryl groups of proteins. I hew results arc discussed in relation lo other epicutaneous tolerizers in the dinitrobenzene and poison ivy systems.