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Amount of nickel applied with a standard patch test
Author(s) -
Fischer Torkel,
Maibach Howard
Publication year - 1984
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1984.tb01011.x
Subject(s) - nickel , patch test , patch testing , materials science , contact dermatitis , chemistry , chromatography , nuclear chemistry , metallurgy , medicine , immunology , allergy
The concentration of nickel sulphate was determined in 9‐16 mg test samples from commercially available patch test antigens. With two different manufacturers of 2.5% nickel sulphate in pet, the concentration range of 25 samples was 0.7 and 1.1% (±2 SD) respectively, and with one manufacturer of 5.0% nickel sulphate in pet, the range was ±0.5%. In a normal patch test, the volume of patch test material applied with the Finn chamber technique should be 12–18μl (9–16 mg), but has been found to range between 9 and 50 μl. Thus the amount of nickel applied in standard patch tests varies within at least 6‐fold limits.