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Contact allergy to styrene and related chemicals
Author(s) -
Sjöborg Steinar,
Fregert Sigfred,
Trulsson Lena
Publication year - 1984
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1984.tb00342.x
Subject(s) - styrene , epoxide , chemistry , organic chemistry , styrene oxide , copolymer , catalysis , polymer
One patient, sensitive to styrene, cross‐reacted at patch testing to 2‐, 3‐ and 4‐vinyltoluene (2‐, 3‐ and 4‐methylstyrene) and to the metabolites styrene epoxide and 4‐vinylphenol (4‐hydroxy‐styrene). It is assumed that styrene is a prohapten metabolized in the skin by aryl hydrocarbon hydroxylase (AHH) to styrene epoxide acting as the true hapten. Styrene occurs in nature and as a synthetic product. Vinyltoluenes (methylstyrenes) occur as synthetic products in plastics. 4‐vinylphenol (4‐hydroxystyrene) occurs frequently in different ciders, wines, foods and berries, e.g. cloudberry.