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Reduced skin threshold to irritation in the presence of allergic contact dermatitis in the guinea pig
Author(s) -
Arlette John P.,
Fritzler Marvin J.
Publication year - 1984
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1984.tb00167.x
Subject(s) - irritation , dermatology , contact dermatitis , allergic contact dermatitis , irritant contact dermatitis , skin irritation , guinea pig , hand dermatitis , allergy , medicine , chemistry , immunology
The skin is more susceptible to irritation when an active eczematous process is present. This reduced threshold to irritation occurs in skin distant from the site of the eczematous skin. Data is presented to demonstrate the appearance of irritant dermatitis lo lower concentrations of sodium lauryl sulfate during the presence of an allergic contact dermatitis in the guinea pig.