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24 and 48 h allergen exposure in patch testing
Author(s) -
Kalimo Kirsti,
Lammintausta Kalja
Publication year - 1984
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1984.tb00057.x
Subject(s) - patch test , allergen , cobalt chloride , patch testing , contact dermatitis , medicine , allergy , nickel , dermatology , allergic reaction , allergic contact dermatitis , formaldehyde , cobalt , immunology , chemistry , organic chemistry
Patch test reactions to 11 common contact allergens were studied after 24 h and 48 h occlusion with Finn Chambers in 390 patients. Concordant allergic results were found in 96 cases (74%). In 22 patients (17%), the reaction was positive only after 48 hand in 11 cases (8.5%) only after 24 h exposure. Most of the discordant reactions were to nickel, cobalt, neomycin, formaldehyde and perfume mix. Irritant reactions were found in 55 cases, the majority occurring after 48 h occlusion. Nickel chloride tested in parallel with 48 h exposure lead to more positive allergic and toxic reactions than nickel sulphate.