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Release of nickel into fluids stored in the reservoir of Dermo‐Jets
Author(s) -
Lachapelle J. M.,
Tennstect D.,
Lauwerys R.,
Cromphaut P.,
Armuo F.
Publication year - 1982
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1982.tb04157.x
Subject(s) - nickel , atomic absorption spectroscopy , dimethylglyoxime , chemistry , alopecia areata , nozzle , absorption (acoustics) , chromatography , materials science , dermatology , medicine , organic chemistry , composite material , physics , quantum mechanics , thermodynamics
Release of nickel into triamcinolone acetonide suspensions stored in [he reservoir of a Dermo‐Jet® was demonstrated by electrothermal atomic absorption spectrometry. Increased urinary nickel excretion was found for three days following intradermal injections (with the Dermo‐Jet of triamacinlone acetonide in patients suffering from alopecia areata. The dimethylglyoxime test showed that the internal rod of the reservoir as. well as metallic internal parts of the nozzle leached appreciable amounts of nickel, even before any clinical use.