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Contact allergy to idoxuridine
Author(s) -
Thormann J.,
Wfldenhoff K. E.
Publication year - 1980
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1980.tb05591.x
Subject(s) - idoxuridine , medicine , dermatology , sensitization , contact allergy , allergy , contact dermatitis , immunology , virus
A total of 45 of 60 patients with herpes zoster previously treated with topical idoxuridine 5–40% in dimethylsulfaxide were patch tested 2 years later with idoxuridine 0.5% and 5% in petrolatum. Three (7%) showed positive reactions. Idoxuridine is considered a weak sensitizer, but in strong concentrations and in active solvents, which increases absorption, there seems to be a risk of sensitization.