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Allergenic potential of abietic acid, colophony and pine resin‐HA
Author(s) -
Karlberg AnnTherése.,
Boman Anders,
Wahlberg Jan E.
Publication year - 1980
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1980.tb05571.x
Subject(s) - abietic acid , rosin , resin acid , allergen , chemistry , contact dermatitis , tall oil , organic chemistry , chromatography , allergy , medicine , immunology
Resin acids are considered to be the main allergens in colophony (rosin). Tall oils also contain resin acids and may then be potential sensitizers. A resin acid concentrate (pine resin‐HA) together with Chinese colophony were included in our standard series and applied on 563 patients with contact dermatitis. Fourteen showed an isolated sensitivity to colophony and two to pine resin‐HA. Six patients reacted to both test compounds. Guinea pig maximization tests (Magnusson & Kligman 1969) showed that pine resin‐HA (2 series) was a grade I allergen, abietic acid a grade III allergen and colophony a grade IV allergen. The risk that the resin acids in tall oils would induce contact sensitivity to workers exposed to tall oil‐containing products like cutting fluids and cleansing agents is considered to be minimal.