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Dermatitis associated with Evans blue dye
Author(s) -
Lupton George P.,
Odom Richard B.
Publication year - 1980
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1980.tb04987.x
Subject(s) - evans blue , medicine , dermatology , allergic contact dermatitis , sensitization , contact dermatitis , lymphatic system , evans syndrome , patch test , surgery , pathology , allergy , immunology , antibody , autoimmune hemolytic anemia
A 73‐year‐old woman developed an allergic contact dermatitis of the feet and legs 24 days following lymphangiography. Dermatitis was accompanied by a generalized urticarial reaction. Intracutaneous skin testing was positive lo Evans blue dye, used as a lymphatic marker, but negative to Ethiodol, an iodine‐containing contrast medium. Soft tissue x‐rays revealed extravasated Ethiodol in the left leg but not in the right, while dermatitis occurred on both legs. This finding, combined with the positive skin test to Evans blue, stress the importance of testing with both agents when dermatitis develops following lymphangiography, Intracutancous rather than epicutaneous testing is the indicated route and may be related in the mule of sensitization.