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Petechial reaction following patch testing with cobalt
Author(s) -
Schmidt H.,
Larsen F. Schultz,
Larsen P. Ølholm,
Søgaard H.
Publication year - 1980
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1980.tb03913.x
Subject(s) - petechial rash , infiltration (hvac) , patch testing , irritation , cobalt chloride , vasculitis , cobalt , extravasation , medicine , patch test , pathology , dermatology , allergy , contact dermatitis , chemistry , surgery , materials science , immunology , disease , organic chemistry , composite material
A total of 132 patch tested patients reacted with petechial reactions to cobalt chloride 1 % in petrolatum; 23 were retested with various concentrations of cobalt. In about 60% of those retested the petechial reaction could be reproduced. Histopathological examination showed slight perivascular tymphocytic infiltration, swollen endothelium and extravasation of erythrocytes but no signs of vasculitis. It is suggested that in predisposed patients the petechial reaction following patch testing could be the result of primary irritation.

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