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Triclocarban: Evaluation of contact dermatitis potential in man
Author(s) -
MAJBACH HOWARD,
BANDMANN H.J.,
CALNAN C. D.,
CRONIN E.,
FREGERT S.,
HJORTH N.,
MAGNUSSON B.,
MALTEN K. E.,
MENEGHINI C. L.,
PIRILÄ V.,
WILKINSON D. S.,
JOHANNSEN FREDERICK R.
Publication year - 1978
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1978.tb04559.x
Subject(s) - triclocarban , dermatology , allergic contact dermatitis , contact dermatitis , phototoxicity , medicine , sensitization , triclosan , allergy , chemistry , immunology , pathology , biochemistry , in vitro
Triclocarban was subjected to a profiling of its dermatitis producing potential including irritancy (21–day cumulative irritancy potential and application to 213 normal controls), phototoxicity (method of Marzulli), predictive contact sensitization (modified Draize method), predictive phototesting and buttery screening in 2200 dermatitis patients, in an effort to define its relative dermatitis potential. The allergic contact dermatitis potential of triclocarban following bar soap use appears minimal.