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Immediate and delayed allergic contact reactions to polyethylene glycol
Author(s) -
Fisher Alexander A.
Publication year - 1978
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1978.tb03759.x
Subject(s) - polyethylene glycol , peg ratio , polyethylene , allergic contact dermatitis , allergy , peg 400 , solvent , chemistry , polymer chemistry , dermatology , organic chemistry , medicine , immunology , finance , economics
The lower molecular weight liquid polyethylene glycols (PEG) varying from 200 to 700 are extensively used as solvent vehicles in topical medicaments. Four patients showed allergic reactions‐to these liquid polyethylene glycols in topical medications. Two had immediate urticarial reactions to PEG 400. Two other patients had delayed allergic eczematous reactions, one to PEG 200, and one to PEG 300. Cross reactions occurred between PEG 200. 300 and 400, but not between these liquid polyethylenes and the higher molecular weight solid polyethylenes from 1000 to 6000.