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Routine patch testing with cadmium chloride
Author(s) -
Wahlberg Jan E.
Publication year - 1977
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1111/j.1600-0536.1977.tb03689.x
Subject(s) - cadmium , cadmium chloride , patch test , serial dilution , distilled water , chemistry , atomic absorption spectroscopy , chloride , dilution , cobalt chloride , contact allergy , nuclear chemistry , cobalt , chromatography , contact dermatitis , medicine , inorganic chemistry , allergy , organic chemistry , immunology , pathology , physics , alternative medicine , quantum mechanics , thermodynamics
During a 22‐month period, 2.0% cadmium chloride in distilled water was included in our routine patch test series. Twenty‐five of 1502 eczema patients showed reactions (1.7 %), but none had any relevant history. At serial dilution test only one patient reacted to 1.0 % cadmium; all the other dilutions applied gave negative reactions. Analysis by atomic absorption spectrophotometry of the cadmium chloride used for patch testing showed that it contained less than 1 μg/g of chromium, copper, cobalt and nickel. The conclusion is that no certain case of contact allergy to cadmium chloride has been revealed. An experimental study using the guinea pig maximization test is in progress.